Which side effects are associated with Gentamicin?

Prepare effectively for the NPTE Pharmacology Test with interactive flashcards and multiple-choice questions. Each question is designed with hints and detailed explanations to ensure your readiness for the exam!

Gentamicin is an aminoglycoside antibiotic commonly used to treat serious infections caused by certain bacteria. The side effects associated with Gentamicin primarily include nephrotoxicity and ototoxicity.

Nephrotoxicity refers to damage to the kidneys, which can manifest as elevated serum creatinine levels and reduced urine output. This occurs because aminoglycosides concentrate in renal tissues, leading to potential tubular cell damage.

Ototoxicity involves damage to the inner ear, which can result in hearing loss or balance issues. The risk of ototoxicity is especially significant with prolonged use or at high doses, as Gentamicin can affect the auditory and vestibular functions.

The other options list side effects that are not typically associated with Gentamicin. Rhabdomyolysis and weight gain, ataxia and dizziness, as well as dry mouth and palpitations, relate to other medications or conditions rather than Gentamicin specifically. Understanding these primary side effects can help healthcare providers monitor patients effectively and preemptively address any complications that may arise during treatment.

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