Which of the following reactions is NOT a side effect of Statins?

Statins are a class of medications commonly prescribed to lower cholesterol levels in the blood and help prevent cardiovascular disease. While they are generally well-tolerated, they can lead to several side effects associated with their mechanism of action.

Muscle-related side effects, such as muscle aches and increased creatine kinase (CK) levels, are well-documented adverse effects of statin therapy. Patients may experience myopathy or rhabdomyolysis, which is indicated by elevated CK levels in the blood due to muscle breakdown. Likewise, tea-colored urine may occur as a result of muscle breakdown products entering the urine, particularly in severe cases of rhabdomyolysis.

Hypersensitivity rashes are not commonly associated with statins. While hypersensitivity reactions can occur with any medication, they are not a typical side effect of statins. Rashes generally indicate an allergic reaction, which is more commonly seen with other classes of drugs rather than statins. Therefore, identification of hypersensitivity rash as a non-side effect of statins is the correct assumption in this scenario.