Which of the following medications is NOT associated with addiction?

Cyclobenzaprine is a muscle relaxant commonly used to relieve skeletal muscle spasms and associated pain. Its mechanism primarily involves acting on the central nervous system to produce relaxation effects. Unlike opioids and benzodiazepines, which are well-documented for their potential to lead to physical dependence and addiction due to their effects on the brain's reward and pleasure pathways, cyclobenzaprine does not typically cause these issues.

Opioids bind to specific receptors in the brain, leading to pain relief but also euphoria, which can contribute to misuse and addiction. Benzodiazepines, used for anxiety and sedation, can also create a dependency situation with long-term use, as individuals may develop tolerance and experience withdrawal symptoms if they stop taking them suddenly.

In contrast, cyclobenzaprine has a lower abuse potential, and its use does not commonly lead to physical dependence. Furthermore, antimuscarinics, although used for various conditions such as overactive bladder or motion sickness, are not typically associated with addiction either. Thus, cyclobenzaprine stands out as the medication least likely associated with addiction in this context.