What pharmacological class does lisinopril belong to?

Prepare effectively for the NPTE Pharmacology Test with interactive flashcards and multiple-choice questions. Each question is designed with hints and detailed explanations to ensure your readiness for the exam!

Lisinopril belongs to the class of medications known as ACE inhibitors. This class of drugs functions by inhibiting the angiotensin-converting enzyme (ACE), which plays a crucial role in the renin-angiotensin-aldosterone system. By blocking this enzyme, lisinopril decreases the production of angiotensin II, a potent vasoconstrictor that raises blood pressure. The reduction of angiotensin II results in vasodilation, decreased blood pressure, and a reduction in the workload on the heart.

ACE inhibitors like lisinopril are commonly prescribed for managing high blood pressure and heart failure, as well as for providing renal protection in patients with diabetic nephropathy. The unique mechanism of action of ACE inhibitors distinguishes them from other pharmacological classes. This specificity explains the significant therapeutic role that lisinopril plays in treating cardiovascular conditions, making it a vital medication in managing hypertension and heart failure.

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