What is the primary use of Digitalis, Digitoxin, and Digoxin?

Digitalis, Digitoxin, and Digoxin are primarily used to improve the strength of heart contractions, a property that is particularly beneficial in treating certain types of heart conditions, such as heart failure and atrial fibrillation. These medications belong to a class known as cardiac glycosides, which work by inhibiting the sodium-potassium ATPase pump in cardiac cells. This inhibition leads to an increase in intracellular calcium levels, which enhances the contractility of the heart muscle. Improved contractility allows the heart to pump more effectively, thereby increasing cardiac output and potentially alleviating symptoms related to heart failure.

The effect of these drugs on heart contractions also contributes to a more regulated heart rhythm, particularly in patients with atrial fibrillation, where controlling the force and efficiency of cardiac contractions is crucial for managing symptoms and improving overall heart function. Understanding this primary use is important for healthcare professionals in identifying appropriate treatment pathways for patients with heart-related conditions.