Captopril, Enalapril, and Lisinopril are examples of which class of drugs?

Prepare effectively for the NPTE Pharmacology Test with interactive flashcards and multiple-choice questions. Each question is designed with hints and detailed explanations to ensure your readiness for the exam!

Captopril, Enalapril, and Lisinopril are indeed examples of ACE inhibitors. These medications work by inhibiting the angiotensin-converting enzyme (ACE), which plays a crucial role in the renin-angiotensin-aldosterone system (RAAS). By blocking this enzyme, ACE inhibitors prevent the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. This results in vasodilation, reduced blood pressure, and decreased cardiac workload, making these drugs effective for treating hypertension and heart failure.

Additionally, ACE inhibitors are known to provide renal protection, especially in patients with diabetes, and can help improve outcomes in those with left ventricular dysfunction. Their role in managing cardiovascular disease highlights their significance in pharmacotherapy.

In contrast, thiazide diuretics primarily work by reducing fluid overload through increased urine production, beta blockers primarily reduce heart rate and myocardial oxygen demand, and calcium channel blockers mainly cause vasodilation and reduce cardiac contractility. Understanding the specific mechanisms of these drug classes allows for optimal therapeutic strategies tailored to individual patient needs.

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